N-BOC-β-cyclohexylalanine amide

Base Information

• Chemical Name: N-BOC-β-cyclohexylalanine amide
• CAS No.: 141408-67-5
• Molecular Formula: C₁₄H₂₆N₂O₃
• Molecular Weight: 270.372

Synonyms:N-BOC-β-cyclohexylalanine amide

Chemical Property of N-BOC-β-cyclohexylalanine amide

Chemical Property:

Purity/Quality:

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Technology Process of N-BOC-β-cyclohexylalanine amide

There total 4 articles about N-BOC-β-cyclohexylalanine amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-tert-butoxycarbonylamino-3-cyclohexylpropionic acid (37736-82-6) + isobutyl chloroformate (543-27-1) → N-BOC-β-cyclohexylalanine amide (141408-67-5)

Guidance literature:

With ammonia; triethylamine; In tetrahydrofuran; methanol; ethyl acetate;

Reference yield:

(S)-2-tert-butoxycarbonylamino-3-cyclohexylpropionic acid (37736-82-6) → N-BOC-β-cyclohexylalanine amide (141408-67-5)

Guidance literature:

With Polyphosphorsaeureanhydrid; N,0-dimethylhydroxylamine;

Reference yield:

C17H29NO5 → N-BOC-β-cyclohexylalanine amide (141408-67-5)

Guidance literature:

With ammonium hydroxide; HATU; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.bmcl.2009.07.114

upstream raw materials:

(S)-2-tert-butoxycarbonylamino-3-cyclohexylpropionic acid

N-tert-butoxycarbonyl-L-phenylalanine

isobutyl chloroformate

Downstream raw materials:

C₂₄H₃₆N₂O₇

L-cyclohexylalanine amide

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