4-Amino-1-pentofuranosylquinazolin-2(1h)-one

Base Information

Chemical Name:4-Amino-1-pentofuranosylquinazolin-2(1h)-one
CAS No.:15135-22-5
Molecular Formula:C₁₃H₁₅N₃O₅
Molecular Weight:293.279
Hs Code.:
NSC Number:108606
DSSTox Substance ID:DTXSID70296271

Synonyms:15135-22-5;4-amino-1-pentofuranosylquinazolin-2(1h)-one;NSC108606;SCHEMBL6672068;DTXSID70296271;NSC-108606

Suppliers and Price of 4-Amino-1-pentofuranosylquinazolin-2(1h)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Amino-1-pentofuranosylquinazolin-2(1h)-one

Chemical Property:

Vapor Pressure:6.32E-16mmHg at 25°C
Boiling Point:613.9°Cat760mmHg
Flash Point:325.1°C
Density:1.78g/cm³
XLogP3:-1.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:293.10117059
Heavy Atom Count:21
Complexity:457

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=NC(=O)N2C3C(C(C(O3)CO)O)O)N

Technology Process of 4-Amino-1-pentofuranosylquinazolin-2(1h)-one

There total 8 articles about 4-Amino-1-pentofuranosylquinazolin-2(1h)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1053698-12-6
C₃₄H₂₇N₃O₈

: 15135-22-5
4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one

Guidance literature:: With ammonium hydroxide; In methanol; acetone; at 20 ℃; for 30h;
DOI:10.1248/cpb.52.1422

Reference yield:

: 6974-32-9
1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

: 15135-22-5
4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 1 h / 75 °C

2: 6.78 g / aq. NH₃ / methanol; acetone / 30 h / 20 °C

With ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; In methanol; acetone; acetonitrile;
DOI:10.1248/cpb.52.1422

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 15135-22-5
4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one

Guidance literature:: Multi-step reaction with 6 steps

1: dimethylformamide / 2 h / 20 °C

2: dicyclohexylcarbodiimide / dimethylformamide / 24 h / 20 °C

3: 8.59 g / aq. NH₃ / methanol; dimethylformamide / 24 h / 20 °C

4: acetonitrile / 0.42 h / 75 °C

5: trimethylsilyl trifluoromethanesulfonate / acetonitrile / 1 h / 75 °C

6: 6.78 g / aq. NH₃ / methanol; acetone / 30 h / 20 °C

With ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1248/cpb.52.1422