(E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Base Information

Chemical Name:(E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal
CAS No.:933769-62-1
Molecular Formula:C₂₇H₄₂O₃S
Molecular Weight:446.695
Hs Code.:

Synonyms:(E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Suppliers and Price of (E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

There total 11 articles about (E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₇H₄₄O₃S

: 933769-62-1
(E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Guidance literature:: With pyridinium chlorochromate; In dichloromethane;
DOI:10.1002/anie.200603853

Reference yield:

: C₁₉H₃₆O₄

: 933769-62-1
(E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Guidance literature:: Multi-step reaction with 11 steps

1: CH₃CH₂COOH / 145 °C

2: LiBH₄ / methanol

3: 97 percent / sodium; hexamethylphosphoramide / 2-methyl-propan-2-ol

4: 89 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂

5: NaI / butan-2-one / Heating

6: dimethylformamide / 70 °C

7: 85 percent / HBF₄ / methanol; H₂O

8: (COCl)2; dimethyl sulfoxide; triethylamine / -78 °C

9: 96 percent / CH₂Cl₂ / 22 °C

10: diisobutylaluminum hydride / CH₂Cl₂ / -78 °C

11: pyridinium chlorochromate / CH₂Cl₂

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; lithium borohydride; tetrafluoroboric acid; oxalyl dichloride; sodium; diisobutylaluminium hydride; dimethyl sulfoxide; propionic acid; triethylamine; pyridinium chlorochromate; sodium iodide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; butanone; tert-butyl alcohol; 8: Swern oxidation / 9: Wittig olefination;
DOI:10.1002/anie.200603853

Reference yield:

: 933769-56-3
C₂₁H₄₂O₄

: 933769-62-1
(E)-4-{(1R,2S,3R)-3-Isopropyl-1-methyl-2-[(S)-3-methyl-5-(toluene-4-sulfonyl)-pentyl]-cyclopentyl}-2-methyl-but-2-enal

Guidance literature:: Multi-step reaction with 8 steps

1: 89 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂

2: NaI / butan-2-one / Heating

3: dimethylformamide / 70 °C

4: 85 percent / HBF₄ / methanol; H₂O

5: (COCl)2; dimethyl sulfoxide; triethylamine / -78 °C

6: 96 percent / CH₂Cl₂ / 22 °C

7: diisobutylaluminum hydride / CH₂Cl₂ / -78 °C

8: pyridinium chlorochromate / CH₂Cl₂

With dmap; tetrafluoroboric acid; oxalyl dichloride; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; pyridinium chlorochromate; sodium iodide; In methanol; dichloromethane; water; N,N-dimethyl-formamide; butanone; 5: Swern oxidation / 6: Wittig olefination;
DOI:10.1002/anie.200603853