3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

Base Information

Chemical Name:3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester
CAS No.:863667-03-2
Molecular Formula:C₃₂H₃₅NO₅
Molecular Weight:513.634
Hs Code.:

Synonyms:3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

Suppliers and Price of 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

There total 1 articles about 3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 618901-86-3
3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(pyridin-2-ylsulfanylcarbonyl)-propionic acid tert-butyl ester

: 863667-03-2
3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

Guidance literature:: With copper(l) iodide; In tetrahydrofuran; at -78 - 0 ℃;
DOI:10.1021/ol051287d

Reference yield:

: 863667-03-2
3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

: 863667-06-5
3-amino-4-oxo-6-m-tolyl-hexanoic acid tert-butyl ester

Guidance literature:: With piperidine; In N,N-dimethyl-formamide; for 0.333333h;
DOI:10.1021/ol051287d

Reference yield:

: 863667-03-2
3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-6-m-tolylhexanoic acid tert-butyl ester

: (S)-3-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-carboxy-propionylamino)-4-carboxy-butyrylamino]-3-methyl-butyrylamino}-4-oxo-6-m-tolyl-hexanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: piperidine / dimethylformamide / 0.33 h

2: 55 percent / PyBOP; DIEA / CH₂Cl₂ / 20 °C

3: 98 percent / CF₃CO₂H / 0.17 h / 20 °C

With piperidine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ol051287d