(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylic acid methyl ester

Base Information

Chemical Name:(3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylic acid methyl ester
CAS No.:263769-22-8
Molecular Formula:C14H18ClNO2
Molecular Weight:267.755
Hs Code.:
DSSTox Substance ID:DTXSID80180975
Nikkaji Number:J964.701E,J1.373.936F
Wikipedia:(%2B)-CPCA,(+)-CPCA
Wikidata:Q4540627
ChEMBL ID:CHEMBL296019
Mol file:263769-22-8.mol

Synonyms:(+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate;CPCA ligand;methyl 4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylate;nocaine

Suppliers and Price of (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
(3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester
25 mg
$ 405.00

Biosynth Carbosynth
(3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester
10 mg
$ 203.00

Biosynth Carbosynth
(3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester
5 mg
$ 117.00

Biosynth Carbosynth
(3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester
2 mg
$ 59.00

Biosynth Carbosynth
(3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester
50 mg
$ 704.00

American Custom Chemicals Corporation
(3R,4S)-4-(4-CHLOROPHENYL)-1-METHYLPIPERIDINE-3-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 502.03

Total 46 raw suppliers

Chemical Property of (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylic acid methyl ester

Chemical Property:

Vapor Pressure:7.01E-05mmHg at 25°C
Refractive Index:1.531
Boiling Point:343.5 °C at 760 mmHg
PKA:7.69±0.20(Predicted)
Flash Point:161.5 °C
PSA：29.54000
Density:1.157g/cm³
LogP:2.48620
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:267.1026065
Heavy Atom Count:18
Complexity:290

Purity/Quality:

99%, ^*data from raw suppliers

(3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(C(C1)C(=O)OC)C2=CC=C(C=C2)Cl
Isomeric SMILES:CN1CC[C@@H]([C@H](C1)C(=O)OC)C2=CC=C(C=C2)Cl
Uses (3R,4S)-4-(4-Chlorophenyl)-1-methylpiperidine-3-carboxylicacid methylester is a useful research chemical compound.

Technology Process of (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylic acid methyl ester

There total 8 articles about (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 214335-16-7,205805-13-6
(-)-Methyl 4β-(4-chlorophenyl)-1-methylpiperidine-3β-carboxylate

: 263769-22-8,205805-13-6
(+)-methyl 4β-(4-chlorophenyl)-1-methylpiperidine-3α-carboxylate

Guidance literature:: With sodium methylate; In methanol; Heating;
DOI:10.1016/S0960-894X(00)00308-5

Reference yield: 85.0%

: 263769-22-8,205805-13-6
(+)-methyl 4β-(4-chlorophenyl)-1-methylpiperidine-3α-carboxylate

Guidance literature:

Reference yield:

: 63-75-2
arecoline

: 873-77-8
(4-chlorphenyl)magnesium bromide

: 263769-22-8,205805-13-6
(+)-methyl 4β-(4-chlorophenyl)-1-methylpiperidine-3α-carboxylate

Guidance literature:: arecoline; (4-chlorphenyl)magnesium bromide; In diethyl ether; at -10 ℃;

With O,O'-dibenzoyl-L-tartaric acid; Further stages.;
DOI:10.1021/ja000199f