4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate

Base Information

• Chemical Name: 4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate
• CAS No.: 1190837-96-7
• Molecular Formula: C₁₀H₅Br₂F₃N₂O₃S
• Molecular Weight: 450.031
• Mol file: 1190837-96-7.mol

Synonyms:4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate

Chemical Property of 4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate

There total 1 articles about 4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

trifluoromethylsulfonic anhydride (358-23-6) + 4-bromo-1-(4-bromophenyl)-3-hydroxy-1H-pyrazole (543694-92-4) → 4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate (1190837-96-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2009.07.017

Reference yield: 40.0%

4-bromo-1-(4-bromophenyl)-1H-pyrazol-3-yl trifluoro methanesulfonate (1190837-96-7) + phenylboronic acid (98-80-6) → 1-(biphenyl-4-yl)-3,4-diphenyl-1H-pyrazole (1190838-06-2)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; potassium bromide; In 1,3-dioxane; for 24h; Inert atmosphere; Reflux;

DOI:10.1016/j.tet.2009.07.017

upstream raw materials:

trifluoromethylsulfonic anhydride

4-bromo-1-(4-bromophenyl)-3-hydroxy-1H-pyrazole

Downstream raw materials:

1-(biphenyl-4-yl)-3,4-diphenyl-1H-pyrazole