methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

Base Information

Chemical Name:methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate
CAS No.:405941-25-5
Molecular Formula:C₂₄H₂₆N₂O₄S
Molecular Weight:438.547
Hs Code.:

Synonyms:methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

Suppliers and Price of methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

There total 2 articles about methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 463-49-0
1,2-propanediene

: 280563-07-7
1-methyl-5-iodoindole

: 405941-15-3
N-benzensulfonyl C-allyl glycine methyl ester

: 405941-25-5
methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

Guidance literature:: With tetraethylammonium chloride; potassium carbonate; triphenylphosphine; palladium diacetate; In toluene; at 80 ℃; for 18h; under 750.06 Torr;
DOI:10.1016/S0040-4039(01)01810-X

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 405941-25-5
methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 0 - 20 °C

1.2: 78 percent / triethylamine / CH₂Cl₂ / 16 h / 0 - 20 °C

2.1: potassium carbonate; tetraethylammonium chloride; triphenylphosphine / palladium(II) acetate / toluene / cooling

2.2: 80 percent / toluene / 40 h / 80 °C

With thionyl chloride; tetraethylammonium chloride; potassium carbonate; triphenylphosphine; palladium diacetate; In toluene;
DOI:10.1016/j.tet.2005.08.078

Reference yield: 85.0%

: 405941-25-5
methyl 2-{[2-(1-methyl-1H-indol-5-yl)-2-propenyl](phenylsulfonyl)amino}-4-pentenoate

: methyl 5-(1-methyl-1H-indole-5-yl)-1-(phenylsulfonyl)-1,2,3,6-tetrahydropyridine-2-carboxylate

Guidance literature:: With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In toluene; at 80 ℃; for 5h;
DOI:10.1016/j.tet.2005.08.078