(3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ⁶-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate

Base Information

• Chemical Name: (3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ⁶-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate
• CAS No.: 129299-11-2
• Molecular Formula: C₁₉H₂₉NO₆
• Molecular Weight: 367.442
• Mol file: 129299-11-2.mol

Synonyms:(3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ⁶-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate

Chemical Property of (3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ⁶-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ⁶-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate

There total 1 articles about (3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ⁶-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

acetyl isocyanate (3998-25-2) + fumagillol (35903-52-7,128656-25-7,132746-73-7,108102-51-8) → (3R,4S,5S,6R)-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-5-(oxo-λ6-methyl)-1-oxaspiro[2.5]octan-6-yl acetylcarbamate (129299-11-2)

Guidance literature:

With dmap; In dichloromethane; for 2h;

DOI:10.1248/cpb.40.96

upstream raw materials:

acetyl isocyanate

fumagillol