N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide

Base Information

Chemical Name:N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide
CAS No.:203047-40-9
Molecular Formula:C₂₀H₂₂N₄OS
Molecular Weight:366.487
Hs Code.:
DSSTox Substance ID:DTXSID201328813
ChEMBL ID:CHEMBL1884150

Synonyms:MLS001216095;SCHEMBL6864740;CHEMBL1884150;DTXSID201328813;HMS2871H18;N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide;STK583852;AKOS002810658;AKOS005507267;203047-40-9;SMR000544513;N-[(2Z)-1,3-benzothiazol-2(3H)-ylidene]-2-(4-benzylpiperazin-1-yl)acetamide

Suppliers and Price of N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:366.15143251
Heavy Atom Count:26
Complexity:463

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)CC(=O)NC3=NC4=CC=CC=C4S3

Technology Process of N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide

There total 2 articles about N-(1,3-benzothiazol-2-yl)-2-(4-benzylpiperazin-1-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 2759-28-6
1-phenylmethylpiperazine

: 3028-02-2
N-benzothiazol-2-yl-2-chloroacetamide

: 203047-40-9
2-[2-(4-benzylpiperazin-1-yl)acetylamino]benzothiazole

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 6h;
DOI:10.1016/j.bioorg.2020.104259

Reference yield:

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 203047-40-9
2-[2-(4-benzylpiperazin-1-yl)acetylamino]benzothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / benzene

2: potassium carbonate / acetone

With potassium carbonate; triethylamine; In acetone; benzene;
DOI:10.1016/S1734-1140(12)70878-2