3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

Base Information

Chemical Name:3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide
CAS No.:948350-43-4
Molecular Formula:C₃₄H₄₀N₄O₆S₂
Molecular Weight:664.847
Hs Code.:

3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

Synonyms:3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

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Chemical Property of 3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

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Technology Process of 3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

There total 1 articles about 3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 146720-18-5
5,7-diethyl-[1,6]naphthyridin-2(1H)-one

: 948350-38-7
methanesulphonic acid 4-{2-[(4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-sulphamoyl]-5-methylthiophene-3-yl}-3-methyl-benzyl ester

: 948350-43-4
3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

Guidance literature:: 5,7-diethyl-[1,6]naphthyridin-2(1H)-one; With sodium hydride; In N,N-dimethyl-formamide; at -15 - 20 ℃; for 0.5h;

methanesulphonic acid 4-{2-[(4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)-sulphamoyl]-5-methylthiophene-3-yl}-3-methyl-benzyl ester; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 24h;

Reference yield:

: 948350-43-4
3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide

: 3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-amide

Guidance literature:: 3-[4-(5,7-diethyl-2-oxo-2H-[1,6]naphthyridin-1-ylmethyl)-2-methyl-phenyl]-5-methyl-thiophene-2-sulphonic acid (4,5-dimethyl-isoxazol-3-yl)-(2-methoxy-ethoxymethyl)amide; With hydrogenchloride; water; In ethanol; at 20 ℃; for 3h; Heating / reflux;

With sodium hydrogencarbonate; In water; pH=8;