2-BROMO-4-IODOBENZALDEHYDE

Base Information

• Chemical Name: 2-BROMO-4-IODOBENZALDEHYDE
• CAS No.: 261903-03-1
• Molecular Formula: C7H4BrIO
• Molecular Weight: 310.91
• Hs Code.: 2913000090
• Mol file: 261903-03-1.mol

Synonyms:2-BROMO-4-IODOBENZALDEHYDE;Benzaldehyde, 2-broMo-4-iodo-

Chemical Property of 2-BROMO-4-IODOBENZALDEHYDE

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Melting Point: 112-114 °C
• Refractive Index: 1.696
• Boiling Point: 312.984 °C at 760 mmHg
• Flash Point: 143.088 °C
• PSA: 17.07000
• Density: 2.231 g/cm³
• LogP: 2.86620
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-4-iodobenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-4-IODOBENZALDEHYDE

There total 3 articles about 2-BROMO-4-IODOBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-Bromo-1-(dibromomethyl)-4-iodobenzene (1168153-28-3) → 2-bromo-4-iodobenzaldehyde (261903-03-1)

Guidance literature:

2-Bromo-1-(dibromomethyl)-4-iodobenzene; With potassium acetate; In acetic acid; for 14h; Reflux; Inert atmosphere;

With hydrogenchloride; In water; acetic acid; for 1h; Reflux; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.03.163

Reference yield:

2-bromo-4-iodo-1-methylbenzene (26670-89-3) → 2-bromo-4-iodobenzaldehyde (261903-03-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-bromosuccinimide / CCl₄ / 18 h / Heating

2: acetic acid / 2 h / Heating

With N-Bromosuccinimide; acetic acid; In tetrachloromethane; 2: Sommelet rearrangement;

DOI:10.1021/jo0302758

Reference yield:

2-Bromo-1-bromomethyl-4-iodo-benzene → 2-bromo-4-iodobenzaldehyde (261903-03-1)

Guidance literature:

With acetic acid; for 2h; Heating;

DOI:10.1021/jo0302758

upstream raw materials:

2-bromo-4-iodo-1-methylbenzene

2-Bromo-1-(dibromomethyl)-4-iodobenzene

Downstream raw materials:

2-(2-bromo-4-iodophenyl)-[1,3]dioxolane

4-[N,N-bis(4-methoxyphenyl)amino]-2-bromobenzaldehyde

4'-[N,N-bis(4-methoxyphenyl)amino]-2'-bromostyrene

(3-bromo-4-(1,3-dioxolan-2-yl)phenyl)bis(4-methoxyphenyl)amine