4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]-

Base Information

Chemical Name:4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]-
CAS No.:900513-18-0
Molecular Formula:C₁₆H₁₅N₃O₂
Molecular Weight:281.314
Hs Code.:
DSSTox Substance ID:DTXSID801206021

Synonyms:900513-18-0;4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]-;SCHEMBL2315834;DTXSID801206021;MFCD09261566;AKOS002671708;MCULE-3958016537;6-amino-3-[(4-methoxyphenyl)methyl]quinazolin-4-one;6-Amino-3-[(4-methoxyphenyl)methyl]-4(3H)-quinazolinone

Suppliers and Price of 4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:281.116426730
Heavy Atom Count:21
Complexity:404

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CN2C=NC3=C(C2=O)C=C(C=C3)N

Technology Process of 4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]-

There total 3 articles about 4(3H)-Quinazolinone, 6-amino-3-[(4-methoxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 900513-13-5
3-(4-methoxybenzyl)-6-nitroquinazolin-4-(3H)-one

: 900513-18-0
3-(4-methoxybenzyl)-6-aminoquinazolin-4-(3H)-one

Guidance literature:: With ammonium formate; palladium on activated charcoal; In ethanol; at 80 ℃; for 0.5h; microvawe irradiation;
DOI:10.1016/j.bmcl.2006.04.006

Reference yield:

: 6943-17-5
6-nitroquinazolone

: 900513-18-0
3-(4-methoxybenzyl)-6-aminoquinazolin-4-(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 0.5 h / microvawe irradiation

2: HCO₂NH₄ / Pd/C / ethanol / 0.5 h / 80 °C / microvawe irradiation

With ammonium formate; sodium hydride; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.04.006

Reference yield:

: 824-94-2
p-methoxybenzyl chloride

: 900513-18-0
3-(4-methoxybenzyl)-6-aminoquinazolin-4-(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 0.5 h / microvawe irradiation

2: HCO₂NH₄ / Pd/C / ethanol / 0.5 h / 80 °C / microvawe irradiation

With ammonium formate; sodium hydride; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.04.006