5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on

Base Information

• Chemical Name: 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on
• CAS No.: 81468-41-9
• Molecular Formula: C₂₃H₁₇N₃O₃S₂
• Molecular Weight: 447.538
• Mol file: 81468-41-9.mol

Synonyms:5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on

Chemical Property of 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on

There total 3 articles about 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5-Amino-5,5-diphenyl-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on + 2-nitro-benzaldehyde (552-89-6) → 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on (81468-41-9)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 0.5h; Heating;

DOI:10.1002/ardp.19873200111

Reference yield: 13.4%

3-{N'-[1-(2-Nitro-phenyl)-meth-(E)-ylidene]-hydrazinothiocarbonylsulfanyl}-2,2-diphenyl-propionic acid → 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on (81468-41-9)

Guidance literature:

With pyridine; sulfuric acid; acetic anhydride; In ethanol; at 70 - 90 ℃; for 4h;

DOI:10.1002/ardp.19823150203

Reference yield:

3-(Thiocarbazoyl-thio)-2,2-diphenyl-propionsaeure (81468-06-6) → 5,5-Diphenyl-3-(2-nitrobenzylidenamino)-2-thioxo-tetrahydro-4H-1,3-thiazin-4-on (81468-41-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 48 percent / PCl₃ / 0.17 h / Heating

2: 70 percent / p-TsOH / toluene / 0.5 h / Heating

With toluene-4-sulfonic acid; phosphorus trichloride; In toluene;

DOI:10.1002/ardp.19873200111

upstream raw materials:

2-nitro-benzaldehyde

3-(Thiocarbazoyl-thio)-2,2-diphenyl-propionsaeure