4-Methyl-6-(trifluoromethyl)nicotinic acid

Base Information

• Chemical Name: 4-Methyl-6-(trifluoromethyl)nicotinic acid
• CAS No.: 261635-74-9
• Molecular Formula: C₈H₆F₃NO₂
• Molecular Weight: 205.136
• DSSTox Substance ID: DTXSID50595956
• Wikidata: Q82491071
• Mol file: 261635-74-9.mol

Synonyms:261635-74-9;4-methyl-6-(trifluoromethyl)nicotinic acid;4-METHYL-6-TRIFLUOROMETHYL-NICOTINIC ACID;4-METHYL-6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXYLIC ACID;6-(Trifluoromethyl)-4-methylpyridine-3-carboxylic acid;SCHEMBL6215528;3-Pyridinecarboxylic acid, 4-methyl-6-(trifluoromethyl)-;DTXSID50595956;IJZZCZADLDCJRX-UHFFFAOYSA-N;MFCD11848202;4-methyl-6-(trifluoromethyl)nicotinicacid;DB-067543;D79883;EN300-5313674;Z1269220778

Chemical Property of 4-Methyl-6-(trifluoromethyl)nicotinic acid

Chemical Property:

• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.479
• Boiling Point: 271.273°C at 760 mmHg
• Flash Point: 117.862°C
• PSA: 50.19000
• Density: 1.415g/cm³
• LogP: 2.10700
• Storage Temp.: 2-8°C
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 205.03506292
• Heavy Atom Count: 14
• Complexity: 229

Purity/Quality:

98%min ^*data from raw suppliers

6-(Trifluoromethyl)-4-methylpyridine-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NC=C1C(=O)O)C(F)(F)F

Technology Process of 4-Methyl-6-(trifluoromethyl)nicotinic acid

There total 1 articles about 4-Methyl-6-(trifluoromethyl)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-methyl-6-trifluoromethylpyridin-3-yl ethyl ester + 4-methyl-6-trifluoromethylnicotinic Acid (261635-74-9)

Guidance literature:

Refernces