(3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone

Base Information

• Chemical Name: (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone
• CAS No.: 185686-52-6
• Molecular Formula: C₂₄H₂₇BrO₂
• Molecular Weight: 427.381
• Mol file: 185686-52-6.mol

Synonyms:(3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone

Chemical Property of (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone

There total 5 articles about (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E,E)-8-O-(3-benzoylbenzyl)-3,7-dimethyl-2,6-octadiene-1-ol (185686-49-1) → (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone (185686-52-6)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane;

DOI:10.1016/S0040-4039(96)02066-7

Reference yield:

geranyl 2-tetrahydropyranyl ether (59632-99-4) → (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone (185686-52-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 56 percent / t-BuOOH, H₂SeO₃, salicylic acid / CH₂Cl₂

2: 80 percent / NaH / tetrahydrofuran

3: PPTS / ethanol

4: PPh₃, CBr₄ / CH₂Cl₂

With tert.-butylhydroperoxide; carbon tetrabromide; pyridinium p-toluenesulfonate; selenious acid; sodium hydride; triphenylphosphine; salicylic acid; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1016/S0040-4039(96)02066-7

Reference yield:

(2E,6E)-2,6-dimethyl-8-((tetrahydro-2H-pyran-2-yl)oxy)octa-2,6-dien-1-ol (66408-80-8,70238-39-0,80444-67-3,143590-48-1,38290-53-8) → (3-((((2E,6E)-8-bromo-2,6-dimethylocta-2,6-dien-1-yl)oxy)methyl)phenyl)(phenyl)methanone (185686-52-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / NaH / tetrahydrofuran

2: PPTS / ethanol

3: PPh₃, CBr₄ / CH₂Cl₂

With carbon tetrabromide; pyridinium p-toluenesulfonate; sodium hydride; triphenylphosphine; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1016/S0040-4039(96)02066-7

upstream raw materials:

(E,E)-8-O-(3-benzoylbenzyl)-3,7-dimethyl-2,6-octadiene-1-ol

geranyl 2-tetrahydropyranyl ether

(2E,6E)-2,6-dimethyl-8-((tetrahydro-2H-pyran-2-yl)oxy)octa-2,6-dien-1-ol

Geraniol

Downstream raw materials:

cysteine (S-(E,E)-8-O-(3-benzoylbenzyl)-3,7-dimethyl-2,6-octadiene) methyl ester

YIIKGVFWDPAC(BC₁₀)-OCH₃

C₈₂H₁₂₀N₁₆O₁₉S₂

N-methanesulfonyl cysteine (S-(E,E)-8-O-(3-benzoylbenzyl)-3,7-dimethyl-2,6-octadiene) methyl ester