Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate

Base Information

Chemical Name:Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate
CAS No.:260555-47-3
Molecular Formula:C15H20 F3 N3 O2
Molecular Weight:331.33
Hs Code.:2933599590
DSSTox Substance ID:DTXSID40381860
Mol file:260555-47-3.mol

Synonyms:260555-47-3;Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate;ETHYL 2-[4-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERAZINO]PROPANOATE;1-Piperazineacetic acid, alpha-methyl-4-[5-(trifluoromethyl)-2-pyridinyl]-, ethyl ester;ethyl 2-{4-[5-(trifluoromethyl)pyridin-2-yl]piperazino}propanoate;Ethyl 2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoate;SCHEMBL1705471;DTXSID40381860;2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]propionic acid ethyl ester

Suppliers and Price of Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL 2-[4-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERAZINO]PROPANOATE 95.00%
10G
$ 1757.28

Total 3 raw suppliers

Chemical Property of Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate

Chemical Property:

Boiling Point:405.2±45.0 °C(Predicted)
PKA:5.99±0.29(Predicted)
PSA：45.67000
Density:1.235±0.06 g/cm3(Predicted)
LogP:2.17690
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:331.15076138
Heavy Atom Count:23
Complexity:398

Purity/Quality:

97% ^*data from raw suppliers

ETHYL 2-[4-[5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]PIPERAZINO]PROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)N1CCN(CC1)C2=NC=C(C=C2)C(F)(F)F

Technology Process of Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate

There total 1 articles about Ethyl 2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 132834-58-3
1-[5-(trifluoromethyl)pyridine-2-yl]piperazine

: 535-11-5,41978-69-2
Ethyl 2-bromopropionate

: 260555-47-3
2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]propionic acid ethyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In ethanol; ethyl acetate;

Reference yield:

: tert-butyl (2-(4-aminobenzamido)phenyl)carbamate

: 260555-47-3
2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]propionic acid ethyl ester

: 1257264-13-3
[2-(4-{2-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-propionylamino}-benzoylamino)-phenyl]-carbamic acid tert-butyl ester

Guidance literature:: With hydrogenchloride; NMM; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide;