3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Base Information

Chemical Name:3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine
CAS No.:1373485-53-0
Molecular Formula:C₄₁H₄₉NO₄S
Molecular Weight:651.91
Hs Code.:

Synonyms:3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Suppliers and Price of 3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

There total 4 articles about 3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: diethyl(3,3-dibutyl-8-(5,5-dimethyl-1,3-dioxan-2-yl)-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-6-yl)methylphosphonate

: 4181-05-9
4-(diphenylamino)benzaldehyde

: 1373485-53-0
3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at -10 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1002/adfm.201101897

Reference yield:

: 259139-21-4
3,4-(2′,2′-dibutylpropylene)dioxythiophene

: 1373485-53-0
3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Guidance literature:: Multi-step reaction with 6 steps

1: 2 h / -10 - 20 °C / Inert atmosphere

2: toluene-4-sulfonic acid / toluene / 24 h / Reflux

3: dichloromethane; acetonitrile / 1 h / 20 - 80 °C / Inert atmosphere

4: diethyl ether; chloroform / 12 h / Darkness

5: N,N-dimethyl-formamide / 150 °C / Inert atmosphere

6: potassium tert-butylate / tetrahydrofuran / 1 h / -10 - 20 °C / Inert atmosphere

With potassium tert-butylate; toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene; acetonitrile; 1: Vilsmeier formylation / 6: Wittig-Horner reaction;
DOI:10.1002/adfm.201101897

Reference yield:

: 1373485-42-7
3,3-dibutyl-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepine-6-carbaldehyde

: 1373485-53-0
3,3-dibutyl-6-((E)-2-(5-hexylthiophen-2-yl)vinyl)-3,4-dihydro-8-(5,5-dimethyl-1,3-dioxan-2-yl)-2H-thieno[3,4-b][1,4]dioxepine

Guidance literature:: Multi-step reaction with 7 steps

1: 2 h / -10 - 20 °C / Inert atmosphere

2: toluene-4-sulfonic acid / toluene / 24 h / Reflux

3: dichloromethane; acetonitrile / 1 h / 20 - 80 °C / Inert atmosphere

4: diethyl ether; chloroform / 12 h / Darkness

5: N,N-dimethyl-formamide / 150 °C / Inert atmosphere

6: potassium tert-butylate / tetrahydrofuran / 1 h / -10 - 20 °C / Inert atmosphere

7: hydrogenchloride / tetrahydrofuran; water / 1 h / 20 °C

With hydrogenchloride; potassium tert-butylate; toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; dichloromethane; chloroform; water; N,N-dimethyl-formamide; toluene; acetonitrile; 1: Vilsmeier formylation / 6: Wittig-Horner reaction;
DOI:10.1002/adfm.201101897