1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid

Base Information

Chemical Name:1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid
CAS No.:259243-72-6
Molecular Formula:C12H7 Cl2 F3 N2 O2
Molecular Weight:339.101
Hs Code.:
DSSTox Substance ID:DTXSID60697910
Wikidata:Q82627945
Mol file:259243-72-6.mol

Synonyms:1-[2,6-DICHLORO-4-(FLUOROMETHYL)PHENYL]-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID;DTXSID60697910;A818091;2-[2,6-dichloro-4-(fluoromethyl)phenyl]-5-methyl-pyrazole-3-carboxylic acid

Suppliers and Price of 1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid

Chemical Property:

PSA：55.12000
LogP:4.20450
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:302.0025111
Heavy Atom Count:19
Complexity:336

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C(=C1)C(=O)O)C2=C(C=C(C=C2Cl)CF)Cl

Technology Process of 1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid

There total 1 articles about 1-[2,6-Dichloro-4-(fluoromethyl)phenyl]-3-methyl-1H-pyrazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 259243-71-5
C₁₄H₁₁Cl₂F₃N₂O₂

: 259243-72-6
1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-5-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; for 4h; Reflux;
DOI:10.3184/174751914X13955977912102

Reference yield: 78.9%

: 259243-72-6
1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-5-carboxylic acid

: 84568-64-9
2-(5-fluorouracil-1-yl)-N-(2-hydroxyethyl)acetamide

: 1630952-07-6
2-(2-(5-fluorouracil-1-yl)acetamido)ethyl 1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-5-carboxylate

Guidance literature:: 1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-3-methyl-1H-pyrazole-5-carboxylic acid; With dmap; 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; for 0.5h;

2-(5-fluorouracil-1-yl)-N-(2-hydroxyethyl)acetamide; In N,N-dimethyl-formamide;
DOI:10.3184/174751914X13955977912102