4-Allyloxymethylbenzyl chloride

Base Information

• Chemical Name: 4-Allyloxymethylbenzyl chloride
• CAS No.: 350671-26-0
• Molecular Formula: C₁₁H₁₃ClO
• Molecular Weight: 196.677
• Mol file: 350671-26-0.mol

Synonyms:4-Allyloxymethylbenzyl chloride

Chemical Property of 4-Allyloxymethylbenzyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Allyloxymethylbenzyl chloride

There total 2 articles about 4-Allyloxymethylbenzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

4-Allyloxymethylbenzyl alcohol (350671-25-9) → 4-Allyloxymethylbenzyl chloride (350671-26-0)

Guidance literature:

With [Me₂NCl](+)Cl(-); In acetonitrile; for 0.666667h; Heating;

DOI:10.1055/s-2001-13392

Reference yield:

p-xylylene glycol (589-29-7) → 4-Allyloxymethylbenzyl chloride (350671-26-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / 1 h / 20 °C

1.2: 63.4 percent / tetrahydrofuran / 7 h / 60 °C

2.1: 98.6 percent / [Me₂NCl](+)Cl(-) / acetonitrile / 0.67 h / Heating

With [Me₂NCl](+)Cl(-); sodium hydride; In tetrahydrofuran; acetonitrile;

DOI:10.1055/s-2001-13392

Reference yield: 97.7%

ethyl diethyl malonate (133-13-1) + 4-Allyloxymethylbenzyl chloride (350671-26-0) → Diethyl 2-(4-allyloxymethylbenzyl)-2-ethylmalonate (350671-27-1)

Guidance literature:

ethyl diethyl malonate; With potassium tert-butylate; In toluene; for 0.5h; Heating;

4-Allyloxymethylbenzyl chloride; In toluene; for 6.5h; Heating;

DOI:10.1055/s-2001-13392

upstream raw materials:

4-Allyloxymethylbenzyl alcohol

p-xylylene glycol

Downstream raw materials:

Diethyl 2-(4-allyloxymethylbenzyl)-2-ethylmalonate

5-Ethyl-5-(4-hydroxymethylbenzyl)barbituric acid

5-Ethyl-5-(4-allyloxymethylbenzyl)barbituric acid

5-Ethyl-5-[4-(4-fluoro-3-nitrobenzoyl)oxymethylbenzyl]barbituric acid