methyl 2,6-diamino-4-(tert-butyl)benzoate

Base Information

• Chemical Name: methyl 2,6-diamino-4-(tert-butyl)benzoate
• CAS No.: 912968-70-8
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.287
• Mol file: 912968-70-8.mol

Synonyms:methyl 2,6-diamino-4-(tert-butyl)benzoate

Chemical Property of methyl 2,6-diamino-4-(tert-butyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl 2,6-diamino-4-(tert-butyl)benzoate

There total 1 articles about methyl 2,6-diamino-4-(tert-butyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-tert-butylbenzoate (26537-19-9) → methyl 2,6-diamino-4-(tert-butyl)benzoate (912968-70-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / nitric acid; sulfuric acid / 3 h / 60 °C

2: 100 percent / ammonium formate / palladium on charcoal / ethanol / 2.5 h / 20 °C

With sulfuric acid; nitric acid; ammonium formate; palladium on activated charcoal; In ethanol;

DOI:10.1021/jo061288z

Reference yield:

methyl 2,6-diamino-4-(tert-butyl)benzoate (912968-70-8) → 2,6-diamino-4-(tert-butyl)benzyl alcohol

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/jo061288z

Reference yield:

methyl 2,6-diamino-4-(tert-butyl)benzoate (912968-70-8) → C12H14Cl2O2

Guidance literature:

With copper(l) chloride; sodium nitrite; at 80 ℃;

DOI:10.1016/j.bmcl.2012.11.115

upstream raw materials:

methyl 4-tert-butylbenzoate

Downstream raw materials:

C₁₁H₁₄Cl₂O