2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate

Base Information

• Chemical Name: 2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate
• CAS No.: 1430067-85-8
• Molecular Formula: C₁₅H₂₁FNO₈P
• Molecular Weight: 393.306

Synonyms:2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate

Chemical Property of 2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate

There total 2 articles about 2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C31H33FNO12P (1443987-27-6) → 2-deoxy-2-fluoro-α-D-arabinofuranose (PR)-1-O-phenyl-(methoxy-alaninyl)phosphate (1430067-84-7) + 2-deoxy-2-fluoro-α-D-arabinofuranose (PS)-1-O-phenyl-(methoxy-alaninyl)phosphate (1430067-85-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 2h;

DOI:10.1016/j.bmcl.2013.02.117

Reference yield:

benzyl ((2R,3R,4S)-3-(((benzyloxy)carbonyl)oxy)-4-fluoro-5-hydroxyoxolan-2-yl)methyl carbonate + phenyl methoxyalaninyl phosphorochloridate (142629-80-9) → 2-deoxy-2-fluoro-α-D-arabinofuranose (PR)-1-O-phenyl-(methoxy-alaninyl)phosphate (1430067-84-7) + 2-deoxy-2-fluoro-α-D-arabinofuranose (PS)-1-O-phenyl-(methoxy-alaninyl)phosphate (1430067-85-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tert-butylmagnesium chloride / tetrahydrofuran / 0.33 h / 0 °C

1.2: 0 - 20 °C

2.1: hydrogen; palladium 10% on activated carbon / ethanol / 2 h / 20 °C

With palladium 10% on activated carbon; tert-butylmagnesium chloride; hydrogen; In tetrahydrofuran; ethanol;

DOI:10.1016/j.bmcl.2013.02.117

upstream raw materials:

phenyl methoxyalaninyl phosphorochloridate

C₃₁H₃₃FNO₁₂P

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1430067-85-8 2-deoxy-2-fluoro-α-D-arabinofuranose (P_S)-1-O-phenyl-(methoxy-alaninyl)phosphate

Send

Send

Metric Ton KG G Pound L ML

Send

Send