6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid

Base Information

• Chemical Name: 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid
• CAS No.: 191930-94-6
• Molecular Formula: C₂₀H₂₉NO₅
• Molecular Weight: 363.454
• Mol file: 191930-94-6.mol

Synonyms:6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid

Chemical Property of 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid

There total 1 articles about 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

7-methyl-6-[N-(tert-butyloxycarbonyl)amino]-3-benzyl-1-octen-5-one (191930-91-3) → 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid (191930-94-6)

Guidance literature:

With ruthenium(IV) oxide; sodium periodate; In water; acetone; for 1h; Ambient temperature;

DOI:10.1021/jm950803a

Reference yield:

Boc-Arg(Tos)-OH (13836-37-8) + 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid (191930-94-6) + Nα-[(butyloxycarbonyl)-Nε-(2-chlorobenzyloxycarbonyl)-L-lysyl]-L-aspartic acid β-cyclohexyl ester → Arg-Lys-Asp-Val(k)Phe

Guidance literature:

Multistep reaction;

DOI:10.1021/jm950803a

Reference yield:

trifluoroacetic acid (76-05-1) + 6-methyl-5-[(tert-butyloxycarbonyl)amino]-4-oxo-2-benzylheptanoic acid (191930-94-6) + Nα,Nδ,Nω-tris(benzyloxycarbonyl)-L-arginyl-N-methyl-L-norleucyl-L-aspartic acid β-cyclohexyl ester (151012-08-7) → Arg-NMeNle-Asp-Val(k)Phe*2CF3COOH

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jm950803a

upstream raw materials:

7-methyl-6-[N-(tert-butyloxycarbonyl)amino]-3-benzyl-1-octen-5-one