Benzyl 4-(tert-butoxycarbonyl)benzylcarbamate

Base Information

Chemical Name:Benzyl 4-(tert-butoxycarbonyl)benzylcarbamate
CAS No.:220851-46-7
Molecular Formula:C₂₀H₂₃NO₄
Molecular Weight:341.407
Hs Code.:
DSSTox Substance ID:DTXSID301158297

Synonyms:220851-46-7;BENZYL 4-(TERT-BUTOXYCARBONYL)BENZYLCARBAMATE;tert-Butyl 4-((((benzyloxy)carbonyl)amino)methyl)benzoate;tert-butyl 4-(phenylmethoxycarbonylaminomethyl)benzoate;SCHEMBL7428120;DTXSID301158297;MFCD16620768;SB83418;AM804823;WS-01638;CS-0046866;tert-Butyl4-((((benzyloxy)carbonyl)amino)methyl)benzoate;1,1-Dimethylethyl 4-[[[(phenylmethoxy)carbonyl]amino]methyl]benzoate

Suppliers and Price of Benzyl 4-(tert-butoxycarbonyl)benzylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzyl 4-(tert-butoxycarbonyl)benzylcarbamate

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:341.16270821
Heavy Atom Count:25
Complexity:430

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C1=CC=C(C=C1)CNC(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 4-(tert-butoxycarbonyl)benzylcarbamate

There total 3 articles about Benzyl 4-(tert-butoxycarbonyl)benzylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56-91-7
p-aminomethylbenzoic acid

: 220851-46-7
4-(benzyloxycarbonylaminomethyl)benzoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 56.1 percent / NaHCO₃; NaOH / dioxane; H₂O

2: 74.5 percent / EDCI; DMAP / CH₂Cl₂

With dmap; sodium hydroxide; sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane; water;
DOI:10.1002/jlcr.1163

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 220851-46-7
4-(benzyloxycarbonylaminomethyl)benzoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 56.1 percent / NaHCO₃; NaOH / dioxane; H₂O

2: 74.5 percent / EDCI; DMAP / CH₂Cl₂

With dmap; sodium hydroxide; sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; dichloromethane; water;
DOI:10.1002/jlcr.1163