L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Base Information

Chemical Name:L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester
CAS No.:333362-92-8
Molecular Formula:C₃₆H₄₇N₆O₁₄P
Molecular Weight:818.775
Hs Code.:

Synonyms:L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Suppliers and Price of L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

There total 9 articles about L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 333362-89-3
N-phenylacetoxybenzyloxycarbonyl-L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

: 333362-92-8
L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Guidance literature:: With penicillin G acylase; In methanol; phosphate buffer; at 20 ℃; for 24h; pH=6.8;
DOI:10.1016/S0040-4039(00)02121-3

Reference yield:

: (S)-2-{(S)-3-(Allyloxy-diisopropylamino-phosphanyloxy)-2-[(S)-3-phenyl-2-(4-phenylacetoxy-benzyloxycarbonylamino)-propionylamino]-propionylamino}-propionic acid allyl ester

: 333362-92-8
L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: terazole / acetonitrile; CH₂Cl₂ / 24 h / 20 °C

2: t-BuOOH / acetonitrile; CH₂Cl₂ / 0.17 h / 0 °C

3: 69 percent / penicillin G acylase; aq. KI / aq. phosphate buffer; methanol / 24 h / 20 °C / pH 6.8

With tert.-butylhydroperoxide; penicillin G acylase; terazole; potassium iodide; In methanol; phosphate buffer; dichloromethane; acetonitrile;
DOI:10.1002/1521-3765(20020415)8:8<1879::AID-CHEM1879>3.0.CO;2-5

Reference yield:

: 2-{3-{[3-acetoxy-5-(4-allyloxycarbonylamino-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-allyloxy-phosphanyloxy}-2-[3-phenyl-2-(4-phenylacetoxy-benzyloxycarbonylamino)-propionylamino]-propionylamino}-propionic acid allyl ester

: 333362-92-8
L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: t-BuOOH / acetonitrile; CH₂Cl₂ / 0.17 h / 0 °C

2: 69 percent / penicillin G acylase; aq. KI / aq. phosphate buffer; methanol / 24 h / 20 °C / pH 6.8

With tert.-butylhydroperoxide; penicillin G acylase; potassium iodide; In methanol; phosphate buffer; dichloromethane; acetonitrile;
DOI:10.1002/1521-3765(20020415)8:8<1879::AID-CHEM1879>3.0.CO;2-5