5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate

Base Information

• Chemical Name: 5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate
• CAS No.: 1208390-78-6
• Molecular Formula: C₂₂H₂₄O₄
• Molecular Weight: 352.43
• Mol file: 1208390-78-6.mol

Synonyms:5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate

Chemical Property of 5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate

There total 1 articles about 5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

4-(2-(benzyloxy)phenyl)-1-(ethoxycarbonothioylthio)-4-oxobutyl pivalate (1208390-85-5) → 5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate (1208390-78-6)

Guidance literature:

With dilauryl peroxide; In 1,2-dichloro-ethane; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2009.11.076

Reference yield: 73.0%

5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate (1208390-78-6) → 5-(benzyloxy)-8-bromo-4-oxo-1,2,3,4-tetrahydronaphthalen-1-ylPivalate

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 0 - 20 ℃; for 30h; Inert atmosphere;

DOI:10.1055/s-0036-1588079

Reference yield: 29.0%

5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate (1208390-78-6) → 5-(benzyloxy)-4-hydroxynaphthalen-1-yl pivalate (1208390-87-7)

Guidance literature:

5-(benzyloxy)-4-oxo-1,2,3,4.tetrahydronaphthalen-1-yl pivalate; With N-Bromosuccinimide; In diethyl ether; acetonitrile; at 0 - 20 ℃; for 2.5h; Inert atmosphere;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; Inert atmosphere; Cooling with ice;

DOI:10.1016/j.tetlet.2009.11.076

upstream raw materials:

4-(2-(benzyloxy)phenyl)-1-(ethoxycarbonothioylthio)-4-oxobutyl pivalate

Downstream raw materials:

5-(benzyloxy)-4-hydroxynaphthalen-1-yl pivalate