{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

Base Information

Chemical Name:{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine
CAS No.:1599479-49-8
Molecular Formula:C₃₃H₂₅N₉S
Molecular Weight:579.688
Hs Code.:

Synonyms:{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

There total 12 articles about {2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.7%

: C₂₄H₁₇N₅OS

: 119192-10-8
4-(1H-1,2,4-triazol-1-ylmethyl)aniline

: 1599479-49-8
{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

Guidance literature:: In methanol; Reflux;
DOI:10.1007/s12039-013-0541-4

Reference yield:

: C₅₂H₃₉N₉S

: 1599479-49-8
{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

Guidance literature:: With water; potassium hydroxide; Reflux;
DOI:10.1007/s12039-013-0541-4

Reference yield:

: 5720-05-8
4-methylphenylboronic acid

: 1599479-49-8
{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethylsulphanyl]-quinolin-3-ylmethylene}-(4-[1,2,4]triazol-1-ylmethyl-phenyl)-amine

Guidance literature:: Multi-step reaction with 6 steps

1: palladium diacetate; triethylamine; triphenylphosphine / acetonitrile

2: sodium azide / N,N-dimethyl-formamide

3: potassium hydroxide / methanol

4: bromine; acetic acid

5: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Reflux

6: methanol / Reflux

With sodium azide; bromine; palladium diacetate; potassium carbonate; acetic acid; triethylamine; triphenylphosphine; potassium hydroxide; In methanol; N,N-dimethyl-formamide; acetonitrile; 1: |Suzuki Coupling;
DOI:10.1007/s12039-013-0541-4