(2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

Base Information

Chemical Name:(2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide
CAS No.:383368-61-4
Molecular Formula:C₁₇H₂₂O₅
Molecular Weight:306.359
Hs Code.:

Synonyms:(2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

Suppliers and Price of (2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

There total 6 articles about (2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 110-87-2
3,4-dihydro-2H-pyran

: 383368-55-6
(2S,3S)-3-benzyloxymethyl-2-hydroxy-4-butanolide

: 383368-61-4
(2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

Guidance literature:: With camphor-10-sulfonic acid;
DOI:10.1039/b104920h

Reference yield:

: 383368-53-4
(2S,3R)-3-benzyloxymethyl-1,2,4-butanetriol

: 383368-61-4
(2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / ZnCl₂; 4 Angstroem molecular sieves / diethyl ether

2: Dess-Martin periodinane / CH₂Cl₂

3: NaClO₂; NaH₂PO₄ / 2-methyl-propan-2-ol; H₂O

4: HCl / dioxane

5: 90 percent / CSA

With hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate; 4 A molecular sieve; camphor-10-sulfonic acid; Dess-Martin periodane; zinc(II) chloride; In 1,4-dioxane; diethyl ether; dichloromethane; water; tert-butyl alcohol; 2: Dess-Martin oxidation;
DOI:10.1039/b104920h

Reference yield:

: 797050-33-0
(2S,3S)-3-benzyloxymethyl-2,4-(4-methoxybenzylidenedioxy)butanal

: 383368-61-4
(2S,3S)-3-benzyloxymethyl-2-[(tetrahydro-2H-pyran-2-yl)oxy]-4-butanolide

Guidance literature:: Multi-step reaction with 3 steps

1: NaClO₂; NaH₂PO₄ / 2-methyl-propan-2-ol; H₂O

2: HCl / dioxane

3: 90 percent / CSA

With hydrogenchloride; sodium chlorite; sodium dihydrogenphosphate; camphor-10-sulfonic acid; In 1,4-dioxane; water; tert-butyl alcohol;
DOI:10.1039/b104920h