Artemisone

Base Information

Chemical Name:Artemisone
CAS No.:255730-18-8
Molecular Formula:C₁₉H₃₁NO₆S
Molecular Weight:401.524
Hs Code.:9999999999
UNII:796LMW5BUZ
ChEMBL ID:CHEMBL516268
Metabolomics Workbench ID:144823
NCI Thesaurus Code:C87431
Nikkaji Number:J2.302.887E
Wikidata:Q27266724
Mol file:255730-18-8.mol

Synonyms:artemisone;BAY 44-9585

Suppliers and Price of Artemisone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Artemisone
1 mg
$ 590.00

ChemScene
Artemisone 98.09%
5mg
$ 350.00

ChemScene
Artemisone 98.09%
100mg
$ 2650.00

ChemScene
Artemisone 98.09%
50mg
$ 1650.00

ChemScene
Artemisone 98.09%
10mg
$ 550.00

American Custom Chemicals Corporation
ARTEMISONE 95.00%
5MG
$ 454.93

Total 9 raw suppliers

Chemical Property of Artemisone

Chemical Property:

Boiling Point:536.5±50.0 °C(Predicted)
PKA:2.99±0.20(Predicted)
PSA：82.68000
Density:1.33±0.1 g/cm3(Predicted)
LogP:2.59590
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:1
Exact Mass:401.18720888
Heavy Atom Count:27
Complexity:696

Purity/Quality:

97% ^*data from raw suppliers

Artemisone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)N5CCS(=O)(=O)CC5)C
Isomeric SMILES:C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)N5CCS(=O)(=O)CC5)C

Technology Process of Artemisone

There total 9 articles about Artemisone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 255730-17-7
artemiside

: 255730-18-8
4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]thiomorpholine 1,1-dioxide

Guidance literature:: With tetrapropylammonium perruthennate; 4 A molecular sieve; 4-methylmorpholine N-oxide; In dichloromethane; at 20 ℃;
DOI:10.1002/anie.200503071

Reference yield:

: 39093-93-1
thiomorpholine 1,1-dioxide

: 887195-43-9
C₁₅H₂₃BrO₄

: 255730-18-8
4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]thiomorpholine 1,1-dioxide

Guidance literature:: With triethylamine; In toluene; at 0 - 22 ℃; for 3h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;
DOI:10.1016/j.tet.2018.04.027

Reference yield:

: 39093-93-1
thiomorpholine 1,1-dioxide

: 10-chloroartemisinin

: 255730-18-8
4-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl]thiomorpholine 1,1-dioxide

: 82596-30-3
9,10-dehydrodihydroartemisinin

Guidance literature:: With triethylamine; In toluene; at 0 - 22 ℃; for 1.75h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;
DOI:10.1016/j.tet.2018.04.027