1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Base Information

Chemical Name:1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate
CAS No.:1297137-84-8
Molecular Formula:C₈H₁₀F₃N₂O*C₉H₁₁O₃S
Molecular Weight:406.426
Hs Code.:

Synonyms:1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Suppliers and Price of 1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

There total 8 articles about 1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1297137-82-6
4-(ethyloxy)-2-(trifluoromethyI)pyridine

: 36016-40-7
mesitylenesulfonylhydroxylamine

: 1297137-84-8
1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Guidance literature:: 4-(ethyloxy)-2-(trifluoromethyI)pyridine; mesitylenesulfonylhydroxylamine; In dichloromethane; at 20 ℃;

With water; Cooling;

Reference yield:

: 1297137-00-8
methyl 5-hydroxy-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-carboxylate

: 1297137-84-8
1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Guidance literature:: Multi-step reaction with 7 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 10 h / 20 °C

2.1: potassium phosphate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 4.5 h / 90 °C / Inert atmosphere

3.1: 3-(1-{[3,4-dichloro-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one / N,N-dimethyl-formamide / 1 h / 60 °C

4.1: sodium hydroxide / methanol / 4 h / 50 °C

5.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 2 h / 20 °C

6.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 5 °C

6.2: 3 h / 5 - 20 °C

7.1: dichloromethane / 20 °C

7.2: Cooling

With potassium phosphate; 3-(1-{[3,4-dichloro-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one; sodium hydride; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 1297137-02-0
methyl 7-(trifluoromethyl)-5-{[(trifluoromethyl)sulfonyl]oxy}pyrazolo[1,5-a]pyridine-2-carboxylate

: 1297137-84-8
1-amino-4-(ethyloxy)-2-(triftuoromethyl)pyridinium 2,4,6-trimethylbenzenesulfonate

Guidance literature:: Multi-step reaction with 6 steps

1.1: potassium phosphate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane / 4.5 h / 90 °C / Inert atmosphere

2.1: 3-(1-{[3,4-dichloro-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one / N,N-dimethyl-formamide / 1 h / 60 °C

3.1: sodium hydroxide / methanol / 4 h / 50 °C

4.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 2 h / 20 °C

5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 5 °C

5.2: 3 h / 5 - 20 °C

6.1: dichloromethane / 20 °C

6.2: Cooling

With potassium phosphate; 3-(1-{[3,4-dichloro-5-(methyloxy)-7-(trifluoromethyl)pyrazolo[1,5-a]pyridine-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidin-2-one; sodium hydride; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;