H₂O(C₅H₉N₂O)8C₅H₈O₂(COCF₃)8C₇H₆

Base Information

• Chemical Name: H₂O(C₅H₉N₂O)8C₅H₈O₂(COCF₃)8C₇H₆
• CAS No.: 376648-89-4
• Molecular Formula: C₆₈H₈₈F₂₄N₁₆O₁₉
• Molecular Weight: 1889.5
• Mol file: 376648-89-4.mol

Synonyms:H₂O(C₅H₉N₂O)8C₅H₈O₂(COCF₃)8C₇H₆

Chemical Property of H₂O(C₅H₉N₂O)8C₅H₈O₂(COCF₃)8C₇H₆

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of H₂O(C₅H₉N₂O)8C₅H₈O₂(COCF₃)8C₇H₆

There total 1 articles about H₂O(C₅H₉N₂O)8C₅H₈O₂(COCF₃)8C₇H₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(S)-2-[(S)-2-[(S)-2-[(S)-2-tert-Butoxycarbonylamino-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoic acid (376648-88-3) + (S)-2-[(S)-2-[(S)-2-[(S)-2-Amino-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoic acid benzyl ester; hydrochloride → H2O(C5H9N2O)8C5H8O2(COCF3)8C7H6 (376648-89-4)

Guidance literature:

(S)-2-[(S)-2-[(S)-2-[(S)-2-Amino-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoic acid benzyl ester; hydrochloride; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; N,N-dimethyl-formamide; at -40 ℃; for 1h;

(S)-2-[(S)-2-[(S)-2-[(S)-2-tert-Butoxycarbonylamino-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoic acid; With 4-methyl-morpholine; In tetrahydrofuran; N,N-dimethyl-formamide; at -40 - 20 ℃; Further stages.;

DOI:10.1021/ol0161108

upstream raw materials:

(S)-2-[(S)-2-[(S)-2-[(S)-2-tert-Butoxycarbonylamino-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoylamino]-5-(2,2,2-trifluoro-acetylamino)-pentanoic acid