N-tert-butylpiperazine-1-carboxamide

Base Information

Chemical Name:N-tert-butylpiperazine-1-carboxamide
CAS No.:253175-42-7
Molecular Formula:C9H19 N3 O
Molecular Weight:185.269
Hs Code.:
European Community (EC) Number:828-775-8
DSSTox Substance ID:DTXSID501253942
ChEMBL ID:CHEMBL4590025
Mol file:253175-42-7.mol

Synonyms:N-tert-butylpiperazine-1-carboxamide;253175-42-7;N-(tert-Butyl)piperazine-1-carboxamide;1-Piperazinecarboxamide,N-(1,1-dimethylethyl)-(9CI);SCHEMBL6628000;CHEMBL4590025;DTXSID501253942;(s)-piperazine-2-t-butylcarboxamide;AKOS009216135;AT22984;CS-0224944;EN300-121896;N-(1,1-Dimethylethyl)-1-piperazinecarboxamide

Suppliers and Price of N-tert-butylpiperazine-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
N-Tert-butylpiperazine-1-carboxamide
250mg
$ 391.00

Total 5 raw suppliers

Chemical Property of N-tert-butylpiperazine-1-carboxamide

Chemical Property:

Boiling Point:355.2±31.0 °C(Predicted)
PKA:14.38±0.20(Predicted)
PSA：44.37000
Density:1.011±0.06 g/cm3(Predicted)
LogP:1.05730
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:185.152812238
Heavy Atom Count:13
Complexity:180

Purity/Quality:

98% ^*data from raw suppliers

N-Tert-butylpiperazine-1-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)NC(=O)N1CCNCC1

Technology Process of N-tert-butylpiperazine-1-carboxamide

There total 3 articles about N-tert-butylpiperazine-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₇H₂₅N₃O₃

: 253175-42-7
N-(tert-butyl)piperazine-1-carboxamide

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; N,N-dimethyl-formamide; at 25 ℃;
DOI:10.1021/ol902101c

Reference yield:

: 253175-40-5
tert-butyl 4-(tert-butylcarbamoyl)piperazine-1-carboxylate

: 253175-42-7
N-(tert-butyl)piperazine-1-carboxamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane;
DOI:10.1016/S0960-894X(02)00688-1

Reference yield:

: 1609-86-5
Tert-butyl isocyanate

: 253175-42-7
N-(tert-butyl)piperazine-1-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: iPr₂NEt; DMAP / CH₂Cl₂

2: TFA / CH₂Cl₂

With dmap; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/S0960-894X(02)00688-1