Technology Process of C28H49NO3Si2
There total 4 articles about C28H49NO3Si2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-4-triisopropylsilyl-3-butyn-2-yl mesylate;
With
palladium diacetate; triphenylphosphine;
In
tetrahydrofuran;
at -78 ℃;
for 0.0833333h;
Inert atmosphere;
C15H23NO3Si;
With
diethylzinc;
In
tetrahydrofuran; hexane;
at -78 - -20 ℃;
Inert atmosphere;
With
ammonium chloride;
In
tetrahydrofuran; hexane; water;
Inert atmosphere;
DOI:10.1002/chem.201100180
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: methyllithium / tetrahydrofuran; diethyl ether / 0.25 h / -78 °C / Inert atmosphere
1.2: 0.25 h / -78 °C / Inert atmosphere
1.3: 1.5 h / -78 - 20 °C / Inert atmosphere
2.1: palladium diacetate; triphenylphosphine / tetrahydrofuran / 0.08 h / -78 °C / Inert atmosphere
2.2: -78 - -20 °C / Inert atmosphere
2.3: Inert atmosphere
With
methyllithium; palladium diacetate; triphenylphosphine;
In
tetrahydrofuran; diethyl ether;
DOI:10.1002/chem.201100180
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 20 h / Inert atmosphere
2.1: methyllithium / tetrahydrofuran; diethyl ether / 0.25 h / -78 °C / Inert atmosphere
2.2: 0.25 h / -78 °C / Inert atmosphere
2.3: 1.5 h / -78 - 20 °C / Inert atmosphere
3.1: palladium diacetate; triphenylphosphine / tetrahydrofuran / 0.08 h / -78 °C / Inert atmosphere
3.2: -78 - -20 °C / Inert atmosphere
3.3: Inert atmosphere
With
methyllithium; palladium diacetate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1002/chem.201100180
