ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Base Information

Chemical Name:ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate
CAS No.:1430200-26-2
Molecular Formula:C₁₈H₁₇ClN₂O₃
Molecular Weight:344.798
Hs Code.:

Synonyms:ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Suppliers and Price of ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

There total 4 articles about ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1430104-90-7
(2R)-2-benzyl-3-ethoxy-2-hydroxy-3-oxopropanoic acid

: 95-83-0
4-Chloro-1,2-phenylenediamine

: 1430200-26-2
ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Guidance literature:: With HATU; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 56150-08-4
diethyl α-benzyl α-hydroxymalonate

: 1430200-26-2
ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / ethanol / 20 °C

2: OJ-H / methanol; trifluoroacetic acid / 20 °C / 75007.5 Torr / Resolution of racemate; Supercritical conditions

3: HATU / N,N-dimethyl-formamide / 20 °C

With HATU; potassium hydroxide; In methanol; ethanol; N,N-dimethyl-formamide; trifluoroacetic acid;

Reference yield:

: 607-81-8
diethyl 2-benzylmalonate

: 1430200-26-2
ethyl (2R)-2-(6-chloro-1H-benzimidazole-2-yl)-2-hydroxy-3-phenylpropanoate

Guidance literature:: Multi-step reaction with 4 steps

1: cesium fluoride / N,N-dimethyl-formamide / 72 h

2: potassium hydroxide / ethanol / 20 °C

3: OJ-H / methanol; trifluoroacetic acid / 20 °C / 75007.5 Torr / Resolution of racemate; Supercritical conditions

4: HATU / N,N-dimethyl-formamide / 20 °C

With cesium fluoride; HATU; potassium hydroxide; In methanol; ethanol; N,N-dimethyl-formamide; trifluoroacetic acid;