Diethyl 3-bromophenyl phosphonate, 98 %

Base Information

• Chemical Name: Diethyl 3-bromophenyl phosphonate, 98 %
• CAS No.: 35125-65-6
• Molecular Formula: C10H14 Br O3 P
• Molecular Weight: 293.09
• Hs Code.: 2931900090
• Mol file: 35125-65-6.mol

Synonyms:Phosphonic acid,(3-bromophenyl)-, diethyl ester (9CI); Phosphonic acid, (m-bromophenyl)-,diethyl ester (6CI); (3-Bromophenyl)phosphonic acid diethyl ester; Diethyl(m-bromophenyl)phosphonate

Chemical Property of Diethyl 3-bromophenyl phosphonate, 98 %

Chemical Property:

• PSA: 45.34000
• LogP: 3.34050

Purity/Quality:

95%-98% ^*data from raw suppliers

DIETHYL 3-BROMOPHENYL PHOSPHONATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Diethyl 3-bromophenyl phosphonate, 98 %

There total 10 articles about Diethyl 3-bromophenyl phosphonate, 98 % which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C6H4BrFO3S + phosphonic acid diethyl ester (762-04-9) → (3-bromo-phenyl)phosphonic acid diethyl ester (35125-65-6)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 80 ℃; for 5h; Sealed tube;

DOI:10.1039/d1cc00769f

Reference yield: 85.0%

3-bromobenzene-1-diazonium tetrafluoroborate + phosphonic acid diethyl ester (762-04-9) → (3-bromo-phenyl)phosphonic acid diethyl ester (35125-65-6)

Guidance literature:

With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; (triphenylphosphine)gold(I) chloride; In ethanol; acetonitrile; at 20 ℃; for 4h; Irradiation; Inert atmosphere;

DOI:10.1039/c4sc03092c

Reference yield: 75.0%

1-Bromo-3-iodobenzene (591-18-4) + triethyl phosphite (122-52-1) → (3-bromo-phenyl)phosphonic acid diethyl ester (35125-65-6)

Guidance literature:

palladium diacetate; at 90 ℃; for 20h;

DOI:10.1016/j.bmc.2008.04.015

upstream raw materials:

Diethyl phosphonate

3-bromophenyl trifluoromethanesulfonate

1,3-dibromobenzene

phosphonic acid diethyl ester

Downstream raw materials:

C₁₃H₂₀NO₆P

C₁₃H₂₀NO₆P

2-(3-(diethoxyphosphoryl)phenylamino)acetic acid

3-bromophenylphosphonic Acid

Refernces

• 1、 Zhang, Yiyuan,Chen, Wanting,Tan, Tingting,Gu, Yuang,Zhang, Shuning,Li, Jie,Wang, Yan,Hou, Wei,Yang, Guang,Ma, Peixiang,Xu, Hongtao. "Palladium-catalyzed one-pot phosphorylation of phenols mediated by sulfuryl fluoride". . p. 4588 - 4591. Retrieved 2021/05/17.
• 2、 Andaloussi, Mounir,Lindh, Jonas,Saevmarker, Jonas,Sjoeberg, Per J. R.,Larhed, Mats. "Microwave-promoted palladium(II)-catalyzed C-P bond formation by using arylboronic acids or aryltrifluoroborates". supporting information; experimental part. p. 13069 - 13074. Retrieved 2010/05/19.