C₂₃H₂₅NO₃

Base Information

• Chemical Name: C₂₃H₂₅NO₃
• CAS No.: 1562377-09-6
• Molecular Formula: C₂₃H₂₅NO₃
• Molecular Weight: 363.456
• Mol file: 1562377-09-6.mol

Synonyms:C₂₃H₂₅NO₃

Chemical Property of C₂₃H₂₅NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₅NO₃

There total 3 articles about C₂₃H₂₅NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5,5-dimethyl-3-benzylamino-2-cyclohexen-1-one (889-31-6) + benzyl chloroformate (501-53-1,94274-21-2) → C23H25NO3 (1562377-09-6)

Guidance literature:

5,5-dimethyl-3-benzylamino-2-cyclohexen-1-one; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h; Molecular sieve; Inert atmosphere;

benzyl chloroformate; In tetrahydrofuran; at -78 - 20 ℃; Molecular sieve; Inert atmosphere;

DOI:10.1021/ol4034447

Reference yield:

dimedone (126-81-8) → C23H25NO3 (1562377-09-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid; sodium sulfate / benzene / 85 °C / Sealed tube; Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Molecular sieve; Inert atmosphere

2.2: -78 - 20 °C / Molecular sieve; Inert atmosphere

With n-butyllithium; toluene-4-sulfonic acid; sodium sulfate; In tetrahydrofuran; benzene;

DOI:10.1021/ol4034447

Reference yield:

benzylamine (100-46-9) → C23H25NO3 (1562377-09-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid; sodium sulfate / benzene / 85 °C / Sealed tube; Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Molecular sieve; Inert atmosphere

2.2: -78 - 20 °C / Molecular sieve; Inert atmosphere

With n-butyllithium; toluene-4-sulfonic acid; sodium sulfate; In tetrahydrofuran; benzene;

DOI:10.1021/ol4034447

upstream raw materials:

5,5-dimethyl-3-benzylamino-2-cyclohexen-1-one

benzyl chloroformate

dimedone

benzylamine

Downstream raw materials:

C₃₁H₃₇NO₇Si

C₃₃H₃₅F₆NO₇Si

C₂₉H₃₅NO₅Si

C₂₉H₃₅NO₄Si