4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Base Information

Chemical Name:4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS No.:35017-55-1
Molecular Formula:C₁₆H₁₅NO₅S
Molecular Weight:333.365
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80415395
Mol file:35017-55-1.mol

Synonyms:35017-55-1;4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid;4-(4-methylphenyl)sulfonyl-2,3-dihydro-1,4-benzoxazine-2-carboxylic acid;4-Tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid;HMS2852E05;MLS001198171;DTXSID80415395;BBL007590;MFCD00269132;STK523492;AKOS002433759;SMR000559379;VS-01682;CS-0318021;4-Tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid;4-(4-methylbenzenesulfonyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Suppliers and Price of 4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 97%
10g
$ 424.00

Crysdot
4-Tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 97%
5g
$ 306.00

American Custom Chemicals Corporation
4-[(4-METHYLPHENYL)SULFONYL]-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-2-CARBOXYLIC ACID 95.00%
5G
$ 2182.95

American Custom Chemicals Corporation
4-[(4-METHYLPHENYL)SULFONYL]-3,4-DIHYDRO-2H-1,4-BENZOXAZINE-2-CARBOXYLIC ACID 95.00%
1G
$ 1273.39

Total 4 raw suppliers

Chemical Property of 4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Chemical Property:

PSA：92.29000
LogP:3.18170
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:333.06709375
Heavy Atom Count:23
Complexity:535

Purity/Quality:

99% ^*data from raw suppliers

4-Tosyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC(OC3=CC=CC=C32)C(=O)O

Technology Process of 4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

There total 4 articles about 4-[(4-methylphenyl)sulfonyl]-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3897-39-0
N-(2-hydroxy-phenyl)-toluene-4-sulfonamide

: 35017-55-1
3,4-dihydro-4-tosyl-2H-1,4-benzoxazin-2-carbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / K₂CO₃ / acetone / 24 h / Heating

2: 10percent NaOH / 16 h / Heating

With sodium hydroxide; potassium carbonate; In acetone;

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 35017-55-1
3,4-dihydro-4-tosyl-2H-1,4-benzoxazin-2-carbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / pyridine / 15 h / Ambient temperature

2: 10percent NaOH / 16 h / Heating

With sodium hydroxide; In pyridine;

Reference yield:

: 82756-71-6
3,4-Dihydro-2H-1,4-benzoxazin-2-carbnsaeuremethylester

: 35017-55-1
3,4-dihydro-4-tosyl-2H-1,4-benzoxazin-2-carbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / pyridine / 15 h / Ambient temperature

2: 10percent NaOH / 16 h / Heating

With sodium hydroxide; In pyridine;