5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2'-DEOXYURIDINE

Base Information

Chemical Name:5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2'-DEOXYURIDINE
CAS No.:252337-58-9
Molecular Formula:C₂₀H₂₇F₃N₄O₇
Molecular Weight:492.452
Hs Code.:
Mol file:252337-58-9.mol

Synonyms:5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2’-DEOXYURIDINE

Suppliers and Price of 5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2'-DEOXYURIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2’-deoxyuridine
5mg
$ 45.00

Crysdot
TFA-aha-dU 95+%
1g
$ 970.00

Biosynth Carbosynth
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
100 mg
$ 420.00

Biosynth Carbosynth
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
50 mg
$ 300.00

Biosynth Carbosynth
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
25 mg
$ 175.00

Biosynth Carbosynth
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
10 mg
$ 100.00

Biosynth Carbosynth
5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
5 mg
$ 70.00

Total 13 raw suppliers

Chemical Property of 5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2'-DEOXYURIDINE

Chemical Property:

PKA:8.73±0.10(Predicted)
PSA：162.75000
Density:1.435±0.06 g/cm3(Predicted)
LogP:0.32740
Solubility.:DMSO; Methanol; Pyridine; Isopropyl Alcohol

Purity/Quality:

97% ^*data from raw suppliers

5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2’-deoxyuridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido]-2’-deoxyuridine is a derivative of 5-[3-(Trifluoroacetamido)-E-1-propenyl]-2’-deoxyuridine (T785010), which can be used as reactant/reagent for "Corey''s reagent," 3,5-di-tert-butyl-1,2-benzoquinone, as a modifying agent in the synthesis of fluorescent and double-headed nucleosides.

Technology Process of 5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2'-DEOXYURIDINE

There total 1 articles about 5-[N-(6-(TRIFLUOROACETAMIDO)HEXYL)-3(E)-ACRYLAMIDO]-2'-DEOXYURIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 54-42-2,162239-35-2
5-Iodo-2'-deoxyuridine

: 124022-79-3
N-acryloyl-N'-trifluoroacetyl-1,6-diaminohexane

: 252337-58-9
(E)-3-{1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl}-N-[6-(2,2,2-trifluoroacetamido)hexyl]acrylamide

Guidance literature:: 5-Iodo-2'-deoxyuridine; With t r i s ( 4 , 4 ’-methoxydibenzylideneacetone)dipalladium(0); tetrabutylammomium bromide; In N,N-dimethyl-formamide; at 80 ℃; for 0.0833333h;

N-acryloyl-N'-trifluoroacetyl-1,6-diaminohexane; With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 3h;
DOI:10.1055/s-0034-1379962