2,4-Dichloro-7-nitroquinazoline

Base Information

Chemical Name:2,4-Dichloro-7-nitroquinazoline
CAS No.:129112-65-8
Molecular Formula:C₈H₃Cl₂N₃O₂
Molecular Weight:244.037
Hs Code.:
DSSTox Substance ID:DTXSID701304090

Synonyms:2,4-dichloro-7-nitroquinazoline;129112-65-8;Quinazoline, 2,4-dichloro-7-nitro-;Quinazoline, 2,?4-?dichloro-?7-?nitro-;SCHEMBL8129389;DTXSID701304090;MFCD18157742;BS-49569;CS-0141014;E76104;A904923

Suppliers and Price of 2,4-Dichloro-7-nitroquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dichloro-7-nitroquinazoline
100mg
$ 195.00

Crysdot
2,4-Dichloro-7-nitroquinazoline 95+%
1g
$ 447.00

Chemenu
2,4-Dichloro-7-nitroquinazoline 95%
1g
$ 422.00

American Custom Chemicals Corporation
2,4-DICHLORO-7-NITROQUINAZOLINE 95.00%
1G
$ 1850.31

American Custom Chemicals Corporation
2,4-DICHLORO-7-NITROQUINAZOLINE 95.00%
250MG
$ 1167.71

Ambeed
2,4-Dichloro-7-nitroquinazoline 95%
1g
$ 268.00

Ambeed
2,4-Dichloro-7-nitroquinazoline 95%
250mg
$ 108.00

Ambeed
2,4-Dichloro-7-nitroquinazoline 95%
100mg
$ 65.00

Alichem
2,4-Dichloro-7-nitroquinazoline
1g
$ 394.20

Total 6 raw suppliers

Chemical Property of 2,4-Dichloro-7-nitroquinazoline

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:242.9602317
Heavy Atom Count:15
Complexity:261

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dichloro-7-nitroquinazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(C=C1[N+](=O)[O-])N=C(N=C2Cl)Cl
Uses 2,4-Dichloro-7-nitroquinazoline is an intermediate used in the synthesis of 4-phenoxy-2-(1-piperazinyl)quinazolines as potent anticonvulsive and antihypoxic agents. It is also used to prepare quinazoline-based stem cell mobilizers targeting chemokine receptor CXCR4.

Technology Process of 2,4-Dichloro-7-nitroquinazoline

There total 5 articles about 2,4-Dichloro-7-nitroquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 174565-63-0
7-nitro-1,2,3,4-tetrahydro-quinazoline-2,4-dione

: 129112-65-8
2,4-dichloro-7-nitroquinazoline

Guidance literature:: With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 140 ℃; for 3h;

Reference yield:

: 619-17-0
4-Nitroanthranilic acid

: 129112-65-8
2,4-dichloro-7-nitroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

2: POCl₃; PCl₅

With phosphorus pentachloride; trichlorophosphate;

Reference yield:

: 2879-79-0
N-(2-methyl-5-nitrophenyl)acetamide

: 129112-65-8
2,4-dichloro-7-nitroquinazoline

Guidance literature:: Multi-step reaction with 4 steps

1: water; potassium permanganate; magnesium sulfate

2: aqueous hydrochloric acid

4: POCl₃; PCl₅

With hydrogenchloride; potassium permanganate; phosphorus pentachloride; water; magnesium sulfate; trichlorophosphate;