5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline

Base Information

Chemical Name:5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline
CAS No.:251649-52-2
Molecular Formula:C9H8 F N3
Molecular Weight:177.18
Hs Code.:2933290090
DSSTox Substance ID:DTXSID40379060
Wikidata:Q72480077
Mol file:251649-52-2.mol

Synonyms:5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline;251649-52-2;5-fluoro-2-imidazol-1-ylaniline;1-(2-Amino-4-fluorophenyl)imidazole;1-(2-Amino-4-fluorophenyl)-1H-imidazole;Maybridge1_008844;Oprea1_817677;SCHEMBL3284515;HMS566J22;DTXSID40379060;MFCD02180945;STL414837;AKOS000222246;AS-9327;SDCCGMLS-0066263.P001;CS-0268901;FT-0620387;EN300-232422;A817676

Suppliers and Price of 5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Fluoro-2-(1H-imidazol-1-yl)aniline
50mg
$ 60.00

TRC
5-Fluoro-2-(1H-imidazol-1-yl)aniline
10mg
$ 45.00

SynQuest Laboratories
1-(2-Amino-4-fluorophenyl)-1H-imidazole 97%
1 g
$ 122.00

SynQuest Laboratories
1-(2-Amino-4-fluorophenyl)-1H-imidazole 97%
5 g
$ 360.00

SynQuest Laboratories
1-(2-Amino-4-fluorophenyl)-1H-imidazole 97%
10 g
$ 632.00

Matrix Scientific
5-Fluoro-2-(1H-imidazol-1-yl)aniline
1g
$ 179.00

Crysdot
5-Fluoro-2-(1H-imidazol-1-yl)aniline 97%
10g
$ 377.00

CHESS?
MC005628:5-Fluoro-2-imidazol-1-yl-phenylamine 97
1 g
$ 336.00

Chemenu
5-Fluoro-2-(1H-imidazol-1-yl)aniline 97%
10g
$ 356.00

Apolloscientific
5-Fluoro-2-(1H-imidazol-1-yl)aniline 97%
5g
$ 225.00

Total 19 raw suppliers

Chemical Property of 5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline

Chemical Property:

Vapor Pressure:7.01E-05mmHg at 25°C
Melting Point:127 °C
Refractive Index:1.621
Boiling Point:343.5°Cat760mmHg
Flash Point:161.5°C
PSA：43.84000
Density:1.3g/cm³
LogP:2.17480
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:177.07022543
Heavy Atom Count:13
Complexity:176

Purity/Quality:

99%, ^*data from raw suppliers

5-Fluoro-2-(1H-imidazol-1-yl)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)N)N2C=CN=C2
Uses 5-Fluoro-2-(1H-imidazol-1-yl)aniline (cas# 251649-52-2) is a chemical that was found in Burkholderia pseudomallei through fragment screening methods. It is a bacteria that causes melioidosis.

Technology Process of 5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline

There total 2 articles about 5-Fluoro-2-(1H-Imidazol-1-Yl)Aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 25373-42-6
1-(4-fluoro-2-niotrophenyl)-1H-imidazole

: 251649-52-2
1-(2-amino-4-fluorophenyl)-1H-imidazole

Guidance literature:: With tin(ll) chloride; In ethanol; for 30h; Heating;
DOI:10.1021/jm990151g

Reference yield:

: 364-74-9
1,4-difluoro-2-nitrobenzene

: 251649-52-2
1-(2-amino-4-fluorophenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 48 percent / dimethylsulfoxide / 24 h / 50 °C

2: 77 percent / tin(II) chloride dihydrate / ethanol / 30 h / Heating

With tin(ll) chloride; In ethanol; dimethyl sulfoxide; 1: Substitution / 2: Reduction;
DOI:10.1021/jm990151g