2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine

Base Information

• Chemical Name: 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine
• CAS No.: 39504-75-1
• Molecular Formula: C₁₉H₁₃Cl₂NO
• Molecular Weight: 342.224
• Mol file: 39504-75-1.mol

Synonyms:2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine

Chemical Property of 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine

There total 2 articles about 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-11-(4-chloro-phenyl)-dibenzo[b,f][1,4]oxazepine (39504-68-2) → 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine (39504-75-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; under 760 Torr;

Reference yield:

4-chloro-N-[2-(4-chloro-phenoxy)-phenyl]-benzamide (39504-61-5) → 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine (39504-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃, polyphosphoric acid / 130 - 140 °C

2: H₂ / PtO₂ / ethanol / 760 Torr

With PPA; hydrogen; trichlorophosphate; platinum(IV) oxide; In ethanol;

Reference yield:

acetic anhydride (108-24-7) + 2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine (39504-75-1) → 10-acetyl-2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine (39504-82-0)

Guidance literature:

for 8h; Heating;

upstream raw materials:

2-chloro-11-(4-chloro-phenyl)-dibenzo[b,f][1,4]oxazepine

4-chloro-N-[2-(4-chloro-phenoxy)-phenyl]-benzamide

Downstream raw materials:

10-acetyl-2-chloro-11-(4-chloro-phenyl)-10,11-dihydro-dibenzo[b,f][1,4]oxazepine