(2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Base Information

Chemical Name:(2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin
CAS No.:1390643-86-3
Molecular Formula:C₃₆H₄₂O₆Si
Molecular Weight:598.811
Hs Code.:

Synonyms:(2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Suppliers and Price of (2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

There total 12 articles about (2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1390643-83-0
(2R)-4'-(tert-butyldimethylsilyloxy)-5,7-dibenzyloxy-3'-methoxyflavan-3-one

: 1390643-86-3
(2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Guidance literature:: With L-Selectride; In tetrahydrofuran; at -78 ℃; for 8h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol3016463

Reference yield:

: 1390643-77-2
(2R,3S)-4'-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methyl-3-acetylcatechin

: 1390643-86-3
(2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Guidance literature:: Multi-step reaction with 3 steps

1: diisobutylaluminium hydride / toluene / 2 h / -78 °C / Inert atmosphere

2: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere

3: L-Selectride / tetrahydrofuran / 8 h / -78 °C / Inert atmosphere

With L-Selectride; diisobutylaluminium hydride; Dess-Martin periodane; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/ol3016463

Reference yield:

: 1390643-80-7
(2R,3S)-4'-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylcatechin

: 1390643-86-3
(2R,3R)-4'-O-(tert-butyldimethylsilyl)-5,7-di-O-benzyl-3'-O-methylepicatechin

Guidance literature:: Multi-step reaction with 2 steps

1: Dess-Martin periodane / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: L-Selectride / tetrahydrofuran / 8 h / -78 °C / Inert atmosphere

With L-Selectride; Dess-Martin periodane; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol3016463