3-Pyridinecarboxylicacid,5-ethyl-(9CI)

Base Information

• Chemical Name: 3-Pyridinecarboxylicacid,5-ethyl-(9CI)
• CAS No.: 3222-53-5
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.165
• Hs Code.: 2933399090
• Mol file: 3222-53-5.mol

Synonyms:Nicotinicacid, 5-ethyl- (7CI,8CI); 5-Ethyl-3-pyridinecarboxylic acid; 5-Ethylnicotinicacid

Chemical Property of 3-Pyridinecarboxylicacid,5-ethyl-(9CI)

Chemical Property:

• PSA: 50.19000
• LogP: 1.34220

Purity/Quality:

99% ^*data from raw suppliers

5-ethylpyridine-3-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarboxylicacid,5-ethyl-(9CI)

There total 5 articles about 3-Pyridinecarboxylicacid,5-ethyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

5-ethynylnicotinic acid (1211533-87-7) → 5-ethylnicotinate acid (3222-53-5)

Guidance literature:

With 10% palladium on activated carbon; ammonium formate; In methanol; for 12h; Inert atmosphere;

DOI:10.1021/jm1007209

Reference yield: 65.0%

3-Acetyl-5-ethylpyridine (42972-47-4) → 5-ethylnicotinate acid (3222-53-5)

Guidance literature:

With sodium hydroxide; bromine; In water; Ambient temperature;

DOI:10.1016/0008-6215(80)90003-8

Reference yield:

5-acetyl-nicotinic acid ethyl ester (74120-40-4) → 5-ethylnicotinate acid (3222-53-5)

Guidance literature:

With hydrazine hydrate; anschliessendes Behandeln mit KOH;

upstream raw materials:

5-acetyl-nicotinic acid ethyl ester

3-Acetyl-5-ethylpyridine

diethyl 3,5-pyridinedicarboxylate

5-ethynylnicotinic acid

Downstream raw materials:

5-ethyl-1-(3,5-di-O-benzoyl-β-D-ribofuranosyl)-3-methoxycarbonylpyridinium chloride

5-ethyl-1-(3,5-di-O-benzoyl-α-D-ribofuranosyl)-3-methoxycarbonylpyridinium chloride

C₂₉H₃₄N₄O₄