methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride

Base Information

• Chemical Name: methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride
• CAS No.: 857645-71-7
• Molecular Formula: C₂₃H₂₉N₃O₅*ClH
• Molecular Weight: 463.961
• Mol file: 857645-71-7.mol

Synonyms:methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride

Chemical Property of methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride

Chemical Property:

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Technology Process of methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride

There total 1 articles about methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride (857645-71-7)

Guidance literature:

Reference yield:

methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride (857645-71-7) → methyl 3-{2-[((2S)-5-{[(benzyloxy)carbonyl]amino}-2-{[(1-methyl-1H-indol-3-yl)carbonyl]amino}pentanoyl)amino]phenyl}propanoate

Guidance literature:

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In DMF (N,N-dimethyl-formamide); at 5 - 20 ℃; for 12h;

Reference yield:

methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride (857645-71-7) + 2-naphthyl chloroformate (7693-50-7) → 3-{2-[((2S)-5-{[(benzyloxy)carbonyl]amino}-2-{[(2-naphthyloxy)carbonyl]amino}pentanoyl)amino]phenyl}propanoic acid

Guidance literature:

methyl 3-{2-[(2S)-2-amino-5-[benzyloxycarbonylamino]pentanoylamino]phenyl}propanoate hydrochloride; With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 1h;

2-naphthyl chloroformate; In tetrahydrofuran; water; at 4 - 20 ℃;

Refernces