2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-

Base Information

Chemical Name:2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-
CAS No.:253265-98-4
Molecular Formula:C₁₁H₁₃NO₇
Molecular Weight:271.227
Hs Code.:
DSSTox Substance ID:DTXSID801122396
Mol file:253265-98-4.mol

Synonyms:253265-98-4;2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-;SCHEMBL8177881;VCFNCYVHQSHFRH-XSSZXYGBSA-N;DTXSID801122396

Suppliers and Price of 2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione
50mg
$ 1260.00

TRC
1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione
5mg
$ 160.00

Total 6 raw suppliers

Chemical Property of 2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-

Chemical Property:

Boiling Point:391.8±52.0 °C(Predicted)
Density:1.51±0.1 g/cm3(Predicted)
XLogP3:-0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:271.06920175
Heavy Atom Count:19
Complexity:407

Purity/Quality:

99% ^*data from raw suppliers

1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC2C1C(CO2)OC(=O)ON3C(=O)CCC3=O
Isomeric SMILES:C1CO[C@@H]2[C@H]1[C@@H](CO2)OC(=O)ON3C(=O)CCC3=O
Uses 1-[[[[(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione is an impurity of TMC114, a bis-THF-derived compound that acts as an HIV-aspartyl protease inhibitor.

Technology Process of 2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]-

There total 3 articles about 2,5-Pyrrolidinedione, 1-[[[[(3S,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 162020-29-3
Acetic acid (3S,3aR,6aS)-(hexahydro-furo[2,3-b]furan-3-yl) ester

: 253265-98-4
Carbonic acid 2,5-dioxo-pyrrolidin-1-yl ester (3S,3aR,6aS)-(hexahydro-furo[2,3-b]furan-3-yl) ester

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / ethanol

2: Et₃N / CH₂Cl₂

With potassium carbonate; triethylamine; In ethanol; dichloromethane;
DOI:10.1021/jm049560p