cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate

Base Information

• Chemical Name: cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate
• CAS No.: 1025030-51-6
• Molecular Formula: C₃₁H₃₄N₆O₆S
• Molecular Weight: 618.714
• Mol file: 1025030-51-6.mol

Synonyms:cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate

Chemical Property of cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate

There total 1 articles about cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopentyl 3-(6-amino-8-bromo-9H-purin-9-yl)-N-(tert-butoxycarbonyl)-L-phenylalaninate + 3,4-methylenedioxybenzenethiol (5274-08-8) → cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate (1025030-51-6)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 3h;

Reference yield:

cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate (1025030-51-6) → cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-L-phenylalaninate (1025029-35-9)

Guidance literature:

cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

With SCX column;

Reference yield:

cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate (1025030-51-6) → cyclopentyl 4-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate (1025030-56-1)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 60 ℃; for 18h;

upstream raw materials:

3,4-methylenedioxybenzenethiol

Downstream raw materials:

cyclopentyl 4-{6-amino-8-[(1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-L-phenylalaninate

cyclopentyl 4-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)thio]-9H-purin-9-yl}-N-(tert-butoxycarbonyl)-L-phenylalaninate