Technology Process of 5,5'-dibromo-4,4'-bis(oktyl)-2,2'-bithiophene
There total 1 articles about 5,5'-dibromo-4,4'-bis(oktyl)-2,2'-bithiophene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 70 percent / TMEDA; nBuLi; CuCl2 / -78 - 50 °C
2: 82 percent / NBS / CHCl3; acetic acid / 2 h / 0 °C
With
N-Bromosuccinimide; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; copper dichloride;
In
chloroform; acetic acid;
DOI:10.1016/j.tetlet.2006.02.001
- Guidance literature:
-
5,5'-dibromo-4,4'-bis(oktyl)-2,2'-bithiophene;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.666667h;
With
tributyltin chloride;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 2h;
2-[4-bromo-2,5-bis(octyloxy)phenyl]-5-phenyl-1,3,4-oxadiazole;
tetrakis(triphenylphosphine) palladium(0);
In
toluene;
at 20 - 100 ℃;
for 49h;
DOI:10.1021/jo0521596
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 45 percent / K2CO3 / Pd(PPh3)4 / tetrahydrofuran; H2O / 36 h / Heating
2: 91 percent / POCl3 / 1,2-dichloro-ethane / 12 h / Heating
3: 90 percent / Pd(AsPh3)4 / tetrahydrofuran / 24 h / Heating
With
potassium carbonate; trichlorophosphate;
tetrakis(triphenylphosphine) palladium(0); tetrakis(triphenylarsine)palladium(0);
In
tetrahydrofuran; water; 1,2-dichloro-ethane;
1: Suzuki coupling / 2: Vilsmeier-Haack formylation / 3: Stille coupling;
DOI:10.1021/jo070888a
