1,8-Bis(hydroxymethyl)anthracene

Base Information

• Chemical Name: 1,8-Bis(hydroxymethyl)anthracene
• CAS No.: 34824-20-9
• Molecular Formula: C₁₆H₁₄O₂
• Molecular Weight: 238.286
• Hs Code.: 2906299090
• European Community (EC) Number: 678-038-8
• DSSTox Substance ID: DTXSID50514208
• Nikkaji Number: J2.167.375G
• Wikidata: Q82374391
• Mol file: 34824-20-9.mol

Synonyms:1,8-bis(hydroxymethyl)anthracene;anthracene-1,8-dimethanol

Chemical Property of 1,8-Bis(hydroxymethyl)anthracene

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 217 °C
• Refractive Index: 1.741
• Boiling Point: 504.608°C at 760 mmHg
• Flash Point: 249.44°C
• PSA: 40.46000
• Density: 1.286g/cm³
• LogP: 2.97760
• Solubility.: almost transparency in hot EtOH
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 238.099379685
• Heavy Atom Count: 18
• Complexity: 252

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,8-Bis(hydroxymethyl)anthracene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=CC3=C(C=C2C(=C1)CO)C(=CC=C3)CO

Technology Process of 1,8-Bis(hydroxymethyl)anthracene

There total 12 articles about 1,8-Bis(hydroxymethyl)anthracene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

dimethyl anthracene-1,8-dicarboxylate (93655-34-6) → 1,8-bis(hydroxymethyl)anthracene (34824-20-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

Reference yield:

anthracene-1,8-dicarboxylic acid (38378-77-7) → 1,8-bis(hydroxymethyl)anthracene (34824-20-9)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄ / Heating

2: LiAlH₄ / diethyl ether / Heating

With lithium aluminium tetrahydride; sulfuric acid; In diethyl ether;

DOI:10.1246/bcsj.35.1829

Reference yield:

1-Formyl-8-hydroxymethylanthracen (158438-65-4) → 1,8-bis(hydroxymethyl)anthracene (34824-20-9)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.2174/1570180811666140116215724

upstream raw materials:

1,8-diformylanthracene

dimethyl anthracene-1,8-dicarboxylate

anthracene-1,8-dicarboxylic acid

1,8-dichloroanthraquinone

Downstream raw materials:

C₅₂H₄₂P₂⁽²⁺⁾*2Br^(1-)

(8-Bromomethyl-anthracen-1-ylmethyl)-triphenyl-phosphonium; bromide

1-Hydroxymethyl-8-triphenylmethoxymethylanthracen

Refernces

• 1、 -. "Fluorescent molecule for identifying mercury ions as well as preparation method and application". Paragraph 0073; 0089; 0090; 0091. . Retrieved 2019/01/08.