Technology Process of C19H24ClN3O7S
There total 8 articles about C19H24ClN3O7S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-chloro-4-methylsulphonyl-N'-hydroxybenzenecarboximidamide; (2S,3S)-3-[(N-Boc)amino]-4-methoxy-2-methyl-4-oxobutanoic acid;
With
N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
In
dichloromethane;
at 20 ℃;
for 12h;
In
toluene;
for 48h;
Heating / reflux;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogen / palladium(II) hydroxide/carbon / methanol / 3 h / 2068.65 Torr
2.1: N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 12 h / 20 °C
2.2: 48 h / Heating / reflux
With
hydrogen; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
palladium(II) hydroxide/carbon;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: methanol; hexane / 0 - 20 °C
2.1: potassium hexamethylsilazane / tetrahydrofuran; toluene / 1.5 h / -78 °C
3.1: hydrogen / palladium(II) hydroxide/carbon / methanol / 3 h / 2068.65 Torr
4.1: N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane / 12 h / 20 °C
4.2: 48 h / Heating / reflux
With
hydrogen; potassium hexamethylsilazane; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
palladium(II) hydroxide/carbon;
In
tetrahydrofuran; methanol; hexane; dichloromethane; toluene;