3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI)

Base Information

Chemical Name:3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI)
CAS No.:250293-59-5
Molecular Formula:C9H12 O2
Molecular Weight:152.193
Hs Code.:
Mol file:250293-59-5.mol

Synonyms:3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI)

Suppliers and Price of 3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI)

Chemical Property:

PSA：37.30000
LogP:1.06860

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI)

There total 4 articles about 3-Cyclohexene-1-carboxaldehyde, 2-hydroxy-1-methyl-6-methylene- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 250293-58-4
2-(tert-butyldimethylsilyloxy)-1-methyl-6-methylenecyclohex-3-ene-1-carbaldehyde

: 250293-59-5
2-hydroxy-1-methyl-6-methylenecyclohex-3-ene-1-carbaldehyde

Guidance literature:: With acetic acid; at 60 ℃; for 30h;

Reference yield:

: syn,anti-2-hydroxy-1-methyl-6-methylenecyclohex-3-ene-1-carboxylic acid ethyl ester

: 250293-59-5
2-hydroxy-1-methyl-6-methylenecyclohex-3-ene-1-carbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 91 percent / 2,6-dimethylpyridine / CH₂Cl₂ / 15 h / 0 - 20 °C

2: DIBAL-H / hexane / 1 h / -78 °C

3: 95 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / 0.5 h / -60 - -15 °C

4: 70 percent / 85 percent acetic acid / 30 h / 60 °C

With 2,6-dimethylpyridine; oxalyl dichloride; diisobutylaluminium hydride; acetic acid; dimethyl sulfoxide; triethylamine; In hexane; dichloromethane; 1: silylation / 2: Reduction / 3: Oxidation / 4: Hydrolysis;

Reference yield:

: 250293-57-3
[2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-6-methylene-cyclohex-3-enyl]-methanol

: 250293-59-5
2-hydroxy-1-methyl-6-methylenecyclohex-3-ene-1-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / oxalyl chloride; DMSO; Et₃N / CH₂Cl₂ / 0.5 h / -60 - -15 °C

2: 70 percent / 85 percent acetic acid / 30 h / 60 °C

With oxalyl dichloride; acetic acid; dimethyl sulfoxide; triethylamine; In dichloromethane; 1: Oxidation / 2: Hydrolysis;