Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester,

Base Information

Chemical Name:Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester,
CAS No.:250275-27-5
Molecular Formula:C₁₁H₂₀N₂O₂
Molecular Weight:212.292
Hs Code.:
Mol file:250275-27-5.mol

Synonyms:Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester, (1R,6R,7R)-rel- (9CI)

Suppliers and Price of Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester,

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester,

Chemical Property:

PSA：50.36000
LogP:1.83870

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester,

There total 4 articles about Carbamic acid, 3-azabicyclo[4.1.0]hept-7-yl-, 1,1-dimethylethyl ester, which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: [1α,6α,7α]-3-Benzyloxycarbonyl-7-(tert-butoxycarbonyl)amino-3-azabicyclo[4.1.0]heptane

: 250275-27-5,134575-96-5
[1α,6α,7α]-7-(tert-Butoxycarbonyl)amino-3-azabicyclo[4.1.0]heptane

Guidance literature:: With ammonium formate; palladium on activated carbon; In ethanol;

Reference yield:

: 4-benzyl 7-ethyl (1R,6S,7S)-4-azabicyclo[4.1.0]heptane-4,7-dicarboxylate

: 250275-27-5,134575-96-5
[1α,6α,7α]-7-(tert-Butoxycarbonyl)amino-3-azabicyclo[4.1.0]heptane

Guidance literature:: Multi-step reaction with 3 steps

1.1: water; lithium hydroxide monohydrate / methanol; tetrahydrofuran / 16 h / 25 °C

2.1: triethylamine; chloroformic acid ethyl ester / acetone / 0.5 h / 0 °C

2.2: 2 h / 0 - 25 °C

2.3: 12 h / 100 °C

3.1: hydrogen; palladium(II) hydroxide / methanol / 2 h / 25 °C

With lithium hydroxide monohydrate; water; hydrogen; palladium(II) hydroxide; chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; methanol; acetone;

Reference yield:

: [1α,6α,7α]-3-Benzyloxycarbonyl-3-azabicyclo[4.1.0]heptane-7-carboxylic acid

: 250275-27-5,134575-96-5
[1α,6α,7α]-7-(tert-Butoxycarbonyl)amino-3-azabicyclo[4.1.0]heptane

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine; chloroformic acid ethyl ester / acetone / 0.5 h / 0 °C

1.2: 2 h / 0 - 25 °C

1.3: 12 h / 100 °C

2.1: hydrogen; palladium(II) hydroxide / methanol / 2 h / 25 °C

With hydrogen; palladium(II) hydroxide; chloroformic acid ethyl ester; triethylamine; In methanol; acetone;